If you start a new solution (File - New - Solution...), the dialog for a new project does not remember the choosen target framework.
For example (how to reproduce):
Select Category "Windows Application" and choose ".Net Framework 4.0". Now select Category "WPF", the target framework changed to ".Net Framework 4.0 Client Profile". This is reproduceable and should be fixed.
But:
The selected category is stored. Each time I close the dialog and open again, it automatically choose the category "WPF" (the last I had choosen).
This behaiviour is in current stable and also in current trunk from github. (thought to fix it by myself, but I first I want to start with easier parts like translation *g*).